The Asthena Group was launched in June 2021 by the former Iwaki Group under a new holding company structure. In addition to Meltex Inc. which is in the chemicals business, the group consists of companies in the fine chemicals business, pharmaceuticals business, and HBC and food business.
| Corporate name | Astena Holdings Co., Ltd. | |
| Business | Group business management, etc. | |
| Address | 8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-8403, Japan | MAP |
| Phone number | 03-3279-0481 | |
| Home Page | https://www.astena-hd.com/en/ |

| Corporate name | SPERA PHARMA, Inc. | |
| Business | CMC R&D and contract manufacturing of pharmaceutical products | |
| Address | 17-85 Jusohonmachi 2-chome, Yodogawa-ku, Osaka 532-0024,Japan | MAP |
| Phone number | 06-7653-6818 | |
| Home Page | https://www.spera-pharma.co.jp/ |

| Corporate name | SPERA NEXUS, Inc. | |
| Business | Manufacturing and selling of pharmaceutical raw materials and chemical products | |
| Address | 8-2, Nihonbashi Honcho 4-Chome, Chuo-ku, Tokyo 103-0023, Japan | MAP |
| Phone number | 03-3279-0486 | |
| Home page | https://www.spera-nexus.co.jp/ |

| Corporate name | Jitsubo CO., LTD. | |
| Business | Development of peptide synthesis method Molecular Hivinng&trade™ Development of manufacturing processes and technology transfer business related to bulk peptide drugs, etc., as well as contract manufacturing of bulk peptide drugs and licensing of technology |
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| Address | Life Science Research Center 4-1 1-1-43 Suehiro-cho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan | MAP |
| Phone number | 045-633-4327 | |
| Home page | https://www.jitsubo.com/ | |

| Corporate name | IWAKI SEIYAKU CO., LTD. | |
| Business | Manufacture and sale of ethical pharmaceuticals, over-the-counter drugs, veterinary drugs, etc., and contract synthesis of various formulations | |
| Address | 8-2, Nihonbashi-honcho 4-Chome, Chuo-ku, Tokyo 103-0023, Japan | MAP |
| Head office annex | 19-8 Koamicho, Nihonbashi, Chuo-ku, Tokyo 103-8434, Japan | MAP |
| Phone number | 03-3668-1570 | |
| Home page | https://www.iwakiseiyaku.co.jp/ | |

| Corporate name | IWAKI SEIYAKU SAKURA FACTORY CO., LTD. | |
| Business | Manufacture of ethical pharmaceuticals | |
| Address | 2183-1 Teranosaku, Ota, Sakura-shi, Chiba Prefecture 285-0808, Japan | MAP |
| Phone number | 043-485-7111 | |
| Home page | https://www.iwakiseiyaku-sakura.co.jp/ |

| Corporate name | IWAKI & CO., LTD. | |
| Business | Sales of over-the-counter (OTC) pharmaceuticals, cosmetics, food ingredients, manufacture and sales of medical devices and diagnostic products, etc. | |
| Address | 8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-0023, Japan | MAP |
| Phone number | 03-6732-6421 | |
| Home page | https://www.iwaki-kk.co.jp/ |

| Corporate name | APROS Corporation | |
| Business | Manufacturing and sales of cosmetics and health food products | |
| Address | Touka Bldg. 6F, 1-16-1 Ginza, Chuo-ku, Tokyo 104-0061, Japan | MAP |
| Phone Number | 0120-996-996 | |
| Home page | https://www.apros.co.jp/ |

| Corporate name | MarumanH&B Co.,Ltd | |
| Business | Manufacture and sale of health foods, pipo, household goods, and cosmetics | |
| Address | 2F Kanda Tsukasa-machi Building, 2-2-12 Kanda Tsukasa-machi, Chiyoda-ku, Tokyo 101-0048,Japan | MAP |
| Phone Number | 03-3526-9980 | |
| Home Page | https://maruman.co.jp/ |

| Corporate name | Bohen-Kasei Co., Ltd. | |
| Business | Production and sales of food ingredients | |
| Address | 7-9-32 Niikura, Wako, Saitama 351-0115,Japan | MAP |
| Phone Number | 03-3279-0546(Food Ingredients Department, Iwaki Corporation) |

| Corporate name | Astena Heartful Co., Ltd. | |
| Business | Astena Group business consignment | |
| Address | 30-17, Toshima 7-Chome, Kita-ku, Tokyo 114-0003,Japan | MAP |
| Home page | https://www.astena-hd.com/heartful.html |
| Corporate name | Astena Minerva Inc. | |
| Business | Mainly projects related to regional development | |
| Address | 8-2, Nihonbashi Honcho 4-chome, Chuo-ku, Tokyo 103-0023, Japan | MAP |
| Phone number | 03-3279-0483 |